Consumption of systemic antibiotics in the Russian Federation in 2017–2021

Objective. To assess level and the structure of systemic antibiotic consumption in Russia over period 2017 to 2021. Materials Methods. Data were collected analysed compliance with standard protocol World Health Organization Regional Office for Europe by means ATC/DDD methodology J01 group – antibacterials use. Consumption was calculated outpatients inpatients separately as a number DDDs per 1000 inhabitants day (DID) main classes antibiotics agents highest or most diverse levels given time, based on data wholesale purchases public tenders. Results. Antibiotic 2017, 2018, 2019, 2020, 2021 16.6 DID, 14.3 14.8 19 15.7 DID respectively. Penicillins, macrolides lincosamides, quinolones had outpatients. Prominent increase outpatient 2020 related three agents: azithromycin, levofloxacin ceftriaxone. Cephalosporins (mainly III–V generations), penicillins inpatients. Hospital meropenem, tigecycline, vancomycin increased amikacin ciprofloxacin decreased duration study. Conclusions. Levels 2019 relatively low consistent average European Union Economic Area countries. The steep probably due wide use management COVID-19 patients. results study can be value development targeted national stewardship programs awareness campaigns well analysis trends emergence spread resistance.